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Can cannabinoids penetrate the skin?

May 5

Can cannabinoids penetrate the skin?


The new CBD lotion is a 2000mg/CBD 1/5 ratio. It contains 15% arnica and has additional benefits such as shea butter or other essential oils. What is the difference between applying cannabinoids topically and sublingually? Let's see...

Cannabinoids can either be inhaled orally, sublingually and/or orally. CBD is a common ingredient in cosmetic products such as creams and lotions. How do cannabinoids effect the skin? Do they penetrate the protective barrier and reach the deepest layers of the skin?

Can cannabinoids penetrate the skin?

Cannabinoid creams can be applied to the skin and people often believe it enters their body. This is a common belief that can be disproved. It depends. It is possible to apply CBD oil or other cannabinoids directly to the skin using two methods: transdermal, and topical.

Topical application refers specifically to creams and ointments used on the skin’s topmost layers. These products are aimed at the skin, and they do not transport cannabinoids into the blood vessels below.

Transdermal CBD products penetrate the skin's upper layers to reach the bloodstream. Transdermal CBD creams have been shown that they increase plasma levels, which makes CBD easier to access.

Transdermal CBD is not just about rubbing the cannabinoid on your skin. There are several adjuvants needed to make a hydroalcoholic Gel that penetrates the epidermis.

Transdermal cannabisoids have not been extensively studied. However, this method of application might be able to bypass digestion and deliver cannabinoids directly in the bloodstream. This administration is similar to sublingual consumption. Multiple patents have been filed for transdermal cannabis oils.

What are the effects of cannabinoids on skin?

Transdermal delivery delivers cannabinoids directly into your bloodstream. But topical products have an advantage. The skin is a part of the body that has cannabinoid receptacles. The body’s regulatory system, endocannabinoid(ECS), plays an important part and assists many biological processes to maintain homeostasis. Skin is no exception.

Trends In Pharmacological Sciences reported that the skin’s Endocannabinoid Systems play an important role in many processes. External cannabinoids share a similar structure to those in the body. They target the same receptors.

Cannabinoids, dermatological problems

Many studies have been done to examine the effects of cannabis on dermatological conditions. A study was published in Journal of Dermatological Science and examined the effects of cannabis on keratinocyte overproliferation. This condition is often associated to flaky and reddened skin.

These unfavorable symptoms result from the immune system attacking healthy skin cells. This causes rapid skin cell accumulation at the skin's skin surface. CBD, CBN and THC were found to decrease keratinocyte development and restore skin equilibrium. More research is needed to confirm these findings.

Researchers also investigated how cannabinoids could affect the production of sebum. This oily substance can accumulate and cause bacteria to grow in the pores. Research The Journal of Clinical Investigation. The study investigated the effects CBD oil had on human sebocytes (cells which produce too much sebum). CBD could be used to restore normal function in these cells by activating TRPV4 and A2A receptors.

Conclusion: Cannabinoids and skin

While the research on cannabinoids' effects on the skin is still in its infancy stages, it is evident that they have some interesting properties. After discovering the ECS in our largest organ, there have been many questions regarding cannabinoids.