For these engaged in opioid agonist remedy (OAT), cannabis might be an efficient method to scale back fentanyl publicity.

That’s the takeaway from a new study revealed this month within the journal Drug and Alcohol Dependence. 

Drawing information from “two community-recruited potential cohorts of people that use medication in Vancouver, Canada,” the researchers from the College of British Columbia, Heart of Substance Use stated they studied “the connection between hashish use and up to date fentanyl publicity” amongst OAT members between the years 2016 and 2018.

OAT is “an efficient therapy for habit to opioid medication comparable to heroin, oxycodone, hydromorphone (Dilaudid), fentanyl and Percocet,” according to the Canadian research hospital Centre for Addiction and Mental Health, that “includes taking the opioid agonists methadone (Methadose) or buprenorphine (Suboxone)” as a part of an effort to forestall withdrawal and scale back cravings.

The analysis revealed in Drug and Alcohol Dependence was based mostly on “819 members on OAT who contributed 1989 observations over the examine interval.” In accordance with the researchers, fentanyl publicity was “frequent.”

“On the baseline interview, fentanyl was detected in a majority of members,” the researchers wrote, saying that it was detected in 53 % of the members, however that general “hashish use was independently related to diminished probability of being not too long ago uncovered to fentanyl.”

“[W]e discovered that amongst greater than 800 members on OAT in Vancouver, Canada, use of hashish was longitudinally related to a considerably decrease threat of being uncovered to fentanyl. Given the magnitude of the overdose disaster within the U.S. and Canada and the substantial contributions of fentanyl to the burden of overdose morbidity and mortality, findings from this examine assist the experimental analysis of cannabinoids as a possible adjunct remedy to OAT to enhance medical outcomes, significantly to cut back the danger of relapse to illicit opioid use (i.e., fentanyl) and related threat of overdose and demise,” the researchers wrote, as quoted by NORML.

The Function of Hashish In The Opioid Disaster

The examine is the most recent in a rising physique of analysis to recommend that hashish could also be an efficient weapon within the struggle in opposition to the opioid disaster. And because the researchers within the aforementioned examine famous, the “ongoing opioid overdose disaster is pushed largely by publicity to illicitly-manufactured fentanyl.”

In July, a study revealed within the journal Systematic Evaluations discovered “a a lot greater discount in opioid dosage, diminished emergency room visits, and hospital admissions for power non-cancer ache by MC [medical cannabis] customers, in comparison with individuals with no extra use of MC.” 

“There was 64 to 75 % discount in opioid dosage for MC customers and full stoppage of opioid use for power non-cancer ache by 32 to 59 % of MC customers, when in comparison with sufferers with out extra use of MC,” the researchers of that examine wrote.

And in June, research revealed within the Journal of Psychopharmacology discovered “behavioral financial proof that hashish entry might modestly scale back demand for opioids in individuals who’ve ache.”

“Adults reporting present use of opioids for ache administration and previous 30-day hashish publicity…accomplished two hypothetical buy duties by which solely grams of hashish or items of members’ index opioids have been out there for buy, and two hypothetical duties by which each have been concurrently out there and the value of 1 drug elevated whereas the opposite was saved fixed,” the researchers wrote.